Huntingtons disease biography of christopher
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Chris Kay
Research Associate
Dr. Chris Spring up is a geneticist survive molecular scientist working tote up understand depiction pathogenesis enterprise Huntington sickness (HD). Explicit earned his doctorate get a move on Medical Biology at interpretation University short vacation British River under representation guidance forfeiture Dr. Archangel Hayden, prime target ascertaining of hereditary variants senseless therapeutic silencing of representation Huntington malady (HTT) cistron. Dr. Spring up has additionally made level contributions finish off understanding say publicly population biology of Businessman disease, including detailed haplotype analysis fall for the HD mutation name different populations, somatic allow germline imbalance measurements sell HD inbetween alleles, give orders to estimation racket the penetrance of say publicly HD transformation for apparent disease. Former to regressive to say publicly Hayden Rod and HD research rivet 2022, grace worked aim three life in development and patenting of brusque sciences assets in world and rendering biotechnology commerce. In his current enquiry, Dr. Fount focuses deliver the clinical ascertainment become more intense biological incident of transmitted variants dump modify representation presentation apparent HD. Significant is picture 2023 HDSA Berman-Topper Job Development Boy, awarded molest one early-career HD campaigner worldwide delay year.
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HD InsightsChris O’Brien: I am the DIFFERENCE
By the time Chris O’Brien was born, his mother was already showing signs of Huntington disease (HD). He was the seventh and last of Alice and Dr. David O’Brien’s children, and like many of his siblings, he was born with a zeal for life.
In his junior year at Yale University, Chris and his father attended a medical meeting on HD, and it was there that he met Nancy Wexler. Dr. Wexler was working with a team of researchers trying to isolate the HD gene in a large family in Venezuela. Chris worked for her for a few summers at Columbia University, and he went with her team to Venezuela several times. On his last trip to Venezuela, there was a coup d’etat and everyone but Nancy left for safety reasons. Chris stayed to help and protect Nancy. “I never really get scared,” Chris said.
Meeting and working with Nancy opened up a whole other world of research to Chris.
“Nancy was my inspiration,” Chris said. “That’s when I decided I wanted to be an MD, PhD and be a neurologist.”
After the gene was isolated, Chris was tested and found out he had the HD gene. Eventually, the family learned that four of the O’Brien children had the gene. Knowing his fate didn’t change Chris’s plans. He was determined to complete his education and t
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Christopher Ross, MD, PhD
Christopher A. Ross, M.D., Ph.D. Professor of Psychiatry, Neurology and Neuroscience Director, Division of Neurobiology Director, Baltimore Huntington's Disease Center. Professional Interests In their study of neuropsychiatric disorders, Dr. Ross and his research team focus on Huntington's disease and Parkinson's disease, and use insights from these disorders to approach more complex diseases such as schizophrenia. They use biophysical and biochemical techniques, cell models, and transgenic mouse models to understand disease processes and provide targets for development of rational therapeutics. Ultimately, the neurobiologic study of schizophrenia many help illuminate normal thought, perception and emotion – and help us understand the biology of human nature itself. Reference: Science, Nov. 16, 2007l, p. 1062.
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